A historical perspective on the multifunctional outer membrane channel protein TolC in Escherichia coli
Abstract Since its discovery nearly 60 years ago, TolC has been associated with various cellular functions in Escherichia coli, including the efflux of environmental stressors and virulence factors. It also acts as a receptor for specific bacteriophages and the colicin E1 toxin. This review highligh...
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Main Authors: | Mallory Wright, Mandeep Kaur, Laura K. Thompson, Georgina Cox |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2025-01-01
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Series: | npj Antimicrobials and Resistance |
Online Access: | https://doi.org/10.1038/s44259-025-00078-3 |
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