A historical perspective on the multifunctional outer membrane channel protein TolC in Escherichia coli

Abstract Since its discovery nearly 60 years ago, TolC has been associated with various cellular functions in Escherichia coli, including the efflux of environmental stressors and virulence factors. It also acts as a receptor for specific bacteriophages and the colicin E1 toxin. This review highligh...

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Bibliographic Details
Main Authors: Mallory Wright, Mandeep Kaur, Laura K. Thompson, Georgina Cox
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:npj Antimicrobials and Resistance
Online Access:https://doi.org/10.1038/s44259-025-00078-3
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