Accelerated placental aging mediated the association between prenatal exposure to per- and polyfluoroalkyl substances and small-for-gestational age newborns

Accelerated placental aging mediated the association between prenatal exposure to per- and polyfluoroalkyl substances and small-for-gestational age newborns

Whether prenatal exposure to per- and polyfluoroalkyl substances (PFAS) is a risk factor for small-for-gestational-age (SGA) neonates remain elusive, yet even less is known on the role of premature placental aging in this potential adverse effect. In this analysis of 1046 maternal-infant dyads, 30 l...

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Bibliographic Details
Main Authors: Yijun Fan, Liyan Guo, Chang Gao, Yuanyuan Fang, Qiang Zhou, Zhicai Xia, Chengrui Wang, Ruolan Wang, Jia Lv, Lin Tao, Mingliang Fang, Mei Zhao, De-Xiang Xu, Yichao Huang
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Small-for-gestational age
Placental aging
Per- and polyfluoroalkyl substance
Telomere length
Mixture effect
Mediation analysis
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651325006748
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