Increased susceptibility to diet-induced obesity in female mice impairs ovarian steroidogenesis: The role of elevated leptin signalling on nodal activity inhibition in theca cells

Objectives: Susceptibility to obesity in humans is driven by the intricate interplay of genetic, environmental and behavioural factors. Moreover, the mechanisms linking maternal obesity to infertility remain largely understudied. In this study, we investigated how variable susceptibility to obesity...

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Main Authors: Karolina Wołodko, Tjaša Šentjurc, Edyta Walewska, Elżbieta Laniecka, Magdalena Jura, António Galvão
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Molecular Metabolism
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Online Access:http://www.sciencedirect.com/science/article/pii/S2212877824001935
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