TRACKING HER2 TRAFFICKING AND ORGANELLE CROSSTALK IN TRASTUZUMAB-DERUXTECAN–TREATED BREAST CANCER CELLS USING MULTIMODAL IMAGING
Trastuzumab-deruxtecan (T-DXd) is a clinically effective antibody–drug conjugate (ADC) for HER2+ and HER2-low breast cancers, yet its intracellular mechanisms remain elusive. We used a multimodal imaging approach including confocal, immuno-EM, and biochemical assays to investigate T-DXd dynamics in...
Saved in:
| Format: | Article |
|---|---|
| Language: | English |
| Published: |
PAGEPress Publications
2025-08-01
|
| Series: | European Journal of Histochemistry |
| Subjects: | |
| Online Access: | https://www.ejh.it/ejh/article/view/4305 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|