Synthesis, antiproliferative and antiplasmodial evaluation of new chloroquine and mefloquine-based harmiquins

Here we present the synthesis and evaluation of the biological activity of new hybrid compounds, ureido-type (UT) harmiquins, based on chloroquine (CQ) or mefloquine (MQ) scaffolds and β-carboline alkaloid harmine against cancer cell lines and Plasmodium falciparum. The hybrids were prepared from th...

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Bibliographic Details
Main Authors: Pavić Kristina, Poje Goran, Carvalho Lais Pessanha De, Held Jana, Rajić Zrinka
Format: Article
Language:English
Published: Sciendo 2023-12-01
Series:Acta Pharmaceutica
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Online Access:https://doi.org/10.2478/acph-2023-0035
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