IL-10 regulates viral lung immunopathology during acute respiratory syncytial virus infection in mice.

Interleukin (IL-) 10 is a pleiotropic cytokine with broad immunosuppressive functions, particularly at mucosal sites such as the intestine and lung. Here we demonstrate that infection of BALB/c mice with respiratory syncytial virus (RSV) induced IL-10 production by CD4(+) and CD8(+) T cells in the a...

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Bibliographic Details
Main Authors: Jens Loebbermann, Corinna Schnoeller, Hannah Thornton, Lydia Durant, Nathan P Sweeney, Martijn Schuijs, Anne O'Garra, Cecilia Johansson, Peter J Openshaw
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0032371&type=printable
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