The Role of Cathepsin B in Peritoneal Fibrosis due to Peritoneal Dialysis

Glucose-containing peritoneal dialysis (PD) solution causes peritoneal fibrosis (PF) characterized by accumulation of extracellular matrix (ECM) in the submesothelial layer. Cathepsin B is a lysosomal cysteine protease that degrades ECM, but its role in the PF remains unclear. Thus, we investigated...

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Bibliographic Details
Main Authors: Su Ah Sung, Dong Hee Kim, Kook-Hwan Oh, Sang Youb Han, Kum Hyun Han
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:International Journal of Nephrology
Online Access:http://dx.doi.org/10.1155/2019/4150656
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