In Vitro and In Vivo Characterization of a Dual-Function Green Fluorescent Protein–HSV1-Thymidine Kinase Reporter Gene Driven by the Human Elongation Factor 1α Promoter

Toward the goal of monitoring activity of native mammalian promoters with molecular imaging techniques, we stably transfected DU145 prostate carcinoma cells with a fusion construct of enhanced green fluorescent protein (EGFP) and wild-type herpes simplex virus-1 thymidine kinase (HSV1-TK) as a repor...

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Bibliographic Details
Main Authors: Gary D. Luker, Kathryn E. Luker, Vijay Sharma, Christina M. Pica, Julie L. Dahlheimer, Joe A. Ocheskey, Timothy J. Fahrner, Jeffrey Milbrandt, David Piwnica-Worms
Format: Article
Language:English
Published: SAGE Publishing 2002-04-01
Series:Molecular Imaging
Online Access:https://doi.org/10.1162/15353500200201118
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