A review of UK publicly funded non-inferiority trials: is the design more inferior than it should be?

Abstract Background The number of non-inferiority (NI) trials, those aiming to show a new treatment is no worse than a comparator, is increasing. However, their added complexity over superiority trials can create confusion. Most guidance and reviews to date have an industry focus with research sugge...

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Bibliographic Details
Main Authors: Nikki Totton, Steven Julious, Stephen Walters, Elizabeth Coates
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Trials
Subjects:
Online Access:https://doi.org/10.1186/s13063-024-08651-3
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