Toll Like Receptors 4 and 2 Expression in the Bronchial Mucosa of Patients with Cystic Fibrosis
BACKGROUND: Cystic fibrosis (CF) is a lung disease characterized by chronic infection with Gram-negative bacteria Pseudomonas aeruginosa and Gram-positive bacteria Staphylococcus aureus. Recently, toll-like receptor (TLR) 4 has been shown to be responsible for the lipopolysaccharide (LPS)-mediated i...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2005-01-01
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| Series: | Canadian Respiratory Journal |
| Online Access: | http://dx.doi.org/10.1155/2005/648984 |
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| author | Hans-Peter Hauber Meri K Tulic Anne Tsicopoulos Benoit Wallaert Ron Olivenstein Patrick Daigneault Qutayba Hamid |
| author_facet | Hans-Peter Hauber Meri K Tulic Anne Tsicopoulos Benoit Wallaert Ron Olivenstein Patrick Daigneault Qutayba Hamid |
| author_sort | Hans-Peter Hauber |
| collection | DOAJ |
| description | BACKGROUND: Cystic fibrosis (CF) is a lung disease characterized by chronic infection with Gram-negative bacteria Pseudomonas aeruginosa and Gram-positive bacteria Staphylococcus aureus. Recently, toll-like receptor (TLR) 4 has been shown to be responsible for the lipopolysaccharide (LPS)-mediated immune response. While TLR2 mediates responses driven by bacterial lipoproteins and peptidoglycans from Gram-positive bacteria, LPS derived from P aeruginosa may stimulate the immune response in the airways of patients with CF via activation of TLR4. |
| format | Article |
| id | doaj-art-771aec5967be47de99656f87b22b9cda |
| institution | Kabale University |
| issn | 1198-2241 |
| language | English |
| publishDate | 2005-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Respiratory Journal |
| spelling | doaj-art-771aec5967be47de99656f87b22b9cda2025-02-03T00:59:02ZengWileyCanadian Respiratory Journal1198-22412005-01-01121131810.1155/2005/648984Toll Like Receptors 4 and 2 Expression in the Bronchial Mucosa of Patients with Cystic FibrosisHans-Peter Hauber0Meri K Tulic1Anne Tsicopoulos2Benoit Wallaert3Ron Olivenstein4Patrick Daigneault5Qutayba Hamid6Meakins-Christie Laboratories, McGill University, Montreal, Quebec, CanadaMeakins-Christie Laboratories, McGill University, Montreal, Quebec, CanadaU416 Institut National de la Santé et de la Recherche Médicale, Institut Pasteur de Lille and Centre de Soins Mucoviscidose Adulte, Hôpital Calmette, Lille, FranceU416 Institut National de la Santé et de la Recherche Médicale, Institut Pasteur de Lille and Centre de Soins Mucoviscidose Adulte, Hôpital Calmette, Lille, FranceMeakins-Christie Laboratories, McGill University, Montreal, Quebec, CanadaMeakins-Christie Laboratories, McGill University, Montreal, Quebec, CanadaMeakins-Christie Laboratories, McGill University, Montreal, Quebec, CanadaBACKGROUND: Cystic fibrosis (CF) is a lung disease characterized by chronic infection with Gram-negative bacteria Pseudomonas aeruginosa and Gram-positive bacteria Staphylococcus aureus. Recently, toll-like receptor (TLR) 4 has been shown to be responsible for the lipopolysaccharide (LPS)-mediated immune response. While TLR2 mediates responses driven by bacterial lipoproteins and peptidoglycans from Gram-positive bacteria, LPS derived from P aeruginosa may stimulate the immune response in the airways of patients with CF via activation of TLR4.http://dx.doi.org/10.1155/2005/648984 |
| spellingShingle | Hans-Peter Hauber Meri K Tulic Anne Tsicopoulos Benoit Wallaert Ron Olivenstein Patrick Daigneault Qutayba Hamid Toll Like Receptors 4 and 2 Expression in the Bronchial Mucosa of Patients with Cystic Fibrosis Canadian Respiratory Journal |
| title | Toll Like Receptors 4 and 2 Expression in the Bronchial Mucosa of Patients with Cystic Fibrosis |
| title_full | Toll Like Receptors 4 and 2 Expression in the Bronchial Mucosa of Patients with Cystic Fibrosis |
| title_fullStr | Toll Like Receptors 4 and 2 Expression in the Bronchial Mucosa of Patients with Cystic Fibrosis |
| title_full_unstemmed | Toll Like Receptors 4 and 2 Expression in the Bronchial Mucosa of Patients with Cystic Fibrosis |
| title_short | Toll Like Receptors 4 and 2 Expression in the Bronchial Mucosa of Patients with Cystic Fibrosis |
| title_sort | toll like receptors 4 and 2 expression in the bronchial mucosa of patients with cystic fibrosis |
| url | http://dx.doi.org/10.1155/2005/648984 |
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