The role of tribbles homolog 2 in cell proliferation

Abstract Tribbles homolog 2 (TRIB2), a pseudoserine/threonine kinase, is a member of the TRIB family. TRIB2 primarily regulates cell proliferation through its scaffold or adaptor effect on promoting the degradation of target proteins by E3 ligase-dependent ubiquitination and regulating mitogen-activ...

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Bibliographic Details
Main Authors: Wenkang Zhang, Mingkang Li, Minhao Zhang, Gaoliang Yan, Chengchun Tang
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Cell Communication and Signaling
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Online Access:https://doi.org/10.1186/s12964-024-01985-0
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