Dysregulation of gut microbiota stimulates NETs-driven HCC intrahepatic metastasis: therapeutic implications of healthy faecal microbiota transplantation

Dysregulation of gut microbiota stimulates NETs-driven HCC intrahepatic metastasis: therapeutic implications of healthy faecal microbiota transplantation

The stringent regulation of intrahepatic metastases is essential for improving survival outcomes in patients with hepatocellular carcinoma (HCC). This study investigated the impact of gut microbiota on intrahepatic metastasis of HCC and evaluated the therapeutic potential of healthy fecal microbiota...

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Main Authors: Zhe Deng, Si Mei, Zhaoguang Ouyang, Ruoyu Wang, Lihuai Wang, Bo Zou, Jingjing Dai, Kexin Mao, Qian Li, Qianqian Guo, Chun Yi, Fanying Meng, Mingxia Xie, Xue Zhang, Rongrong Wang, Tianhao Deng, Zhenyu Wang, Xiaozheng Li, Qing Wang, Bin Liu, Xuefei Tian
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Gut Microbes
Subjects:
Hepatocellular carcinoma
intrahepatic metastasis
human flora-associated mouse model
neutrophil extracellular traps
healthy faecal microbiota transplantation
Online Access:https://www.tandfonline.com/doi/10.1080/19490976.2025.2476561
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https://www.tandfonline.com/doi/10.1080/19490976.2025.2476561

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