The added value of coupling anti-dsDNA and anti-chromatin antibodies in follow-up monitoring of systemic lupus erythematosus patients

The added value of coupling anti-dsDNA and anti-chromatin antibodies in follow-up monitoring of systemic lupus erythematosus patients

Objective: The autoimmune response to chromatin (Chr) or one of the nucleosome components (double stranded (ds)DNA and histones) is typically associated with the development of systemic lupus erythematosus (SLE). Related autoantibodies (Ab) are heterogeneous and, among them, anti-dsDNA Ab are part o...

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Main Authors: Caroline Carlé, Françoise Fortenfant, Chloé Bost, Julie Belliere, Stanislas Faguer, Dominique Chauveau, Antoine Huart, David Ribes, Laurent Alric, Gregory Pugnet, Laurent Sailler, Yves Renaudineau
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Journal of Translational Autoimmunity
Subjects:
anti-Chromatin
anti-dsDNA
Diagnostic
Flare
Follow-up
SLE
Online Access:http://www.sciencedirect.com/science/article/pii/S2589909025000097
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