Pharmacokinetics of p-Aminohippuric Acid and Inulin in Rabbits with Aristolochic Acid Nephropathy

The characteristics of aristolochic acid nephropathy (AAN) are interstitial fibrosis and atrophy of the proximal tubules, but with no change in glomeruli. To investigate the effects of AA on renal functions and the pharmacokinetics (PKs) of p-aminohippuric acid (PAH) and inulin, New Zealand white ra...

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Bibliographic Details
Main Authors: Chiao-Shih Tseng, Shih-Ming Chen, Shu-Chen Chien, Kuang-Yang Hsu
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Advances in Pharmacological Sciences
Online Access:http://dx.doi.org/10.1155/2011/204501
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