Spinal V1 inhibitory interneuron clades differ in birthdate, projections to motoneurons, and heterogeneity

Spinal V1 inhibitory interneuron clades differ in birthdate, projections to motoneurons, and heterogeneity

Spinal cord interneurons play critical roles shaping motor output, but their precise identity and connectivity remain unclear. Focusing on the V1 interneuron cardinal class we defined four major V1 subsets in the mouse according to neurogenesis, genetic lineage-tracing, synaptic output to motoneuron...

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Bibliographic Details
Main Authors: Andrew E Worthy, Joanna T Anderson, Alicia R Lane, Laura J Gomez-Perez, Anthony A Wang, Ronald W Griffith, Andre F Rivard, Jay B Bikoff, Francisco J Alvarez
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2024-11-01
Series:eLife
Subjects:
spinal cord
motor
Foxp2
limb control
reciprocal inhibition
Renshaw cell
Online Access:https://elifesciences.org/articles/95172
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https://elifesciences.org/articles/95172

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