Treatment strategies for combining immunostimulatory oncolytic virus therapeutics with dendritic cell injections
Oncolytic viruses (OVs) are used to treat cancer, as they selectively replicate inside of and lyse tumor cells. The efficacy of this process is limited and new OVs are being designed to mediate tumor cell release of cytokines and co-stimulatory molecules, which attract cytotoxic T cells to target tu...
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Main Authors: | Joanna R. Wares, Joseph J. Crivelli, Chae-Ok Yun, Il-Kyu Choi, Jana L. Gevertz, Peter S. Kim |
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Format: | Article |
Language: | English |
Published: |
AIMS Press
2015-07-01
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Series: | Mathematical Biosciences and Engineering |
Subjects: | |
Online Access: | https://www.aimspress.com/article/doi/10.3934/mbe.2015.12.1237 |
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