Methamphetamine exposure during gestation and lactation periods impairs the learning and memory of offspring mice, which is reversed by melatonin: the role of oxidative stress and acetylcholinesterase

Methamphetamine exposure during gestation and lactation periods impairs the learning and memory of offspring mice, which is reversed by melatonin: the role of oxidative stress and acetylcholinesterase

Background and purpose: Melatonin is a product of the pineal gland, which regulates the circadian cycle. Neurotoxicity is the most important side effect of methamphetamine (Met) abuse during pregnancy. This study aimed to explore the effect of Met exposure during gestation and lactation periods on t...

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Main Authors: Fatemeh Ghorbani, Negar Osatd-Rahimi, Fatemeh Mansouritorghabeh, Alireza Ebrahimzadeh-bideskan, Ehsan Saburi, Arezoo Rajabian, Mahmoud Hosseini
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-03-01
Series:Research in Pharmaceutical Sciences
Subjects:
acetylcholinesterase
methamphetamine
melatonin
oxidative stress
Online Access:https://journals.lww.com/10.4103/RPS.RPS_187_23
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https://journals.lww.com/10.4103/RPS.RPS_187_23

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