Synergistic influences of BMP9 and NGF on the osteogenic differentiation of C3H10T1/2 mesenchymal stem cells

Synergistic influences of BMP9 and NGF on the osteogenic differentiation of C3H10T1/2 mesenchymal stem cells

Abstract Background Bone morphogenetic protein 9 (BMP9) and nerve growth factor (NGF) are critical factors influencing osteogenic differentiation in mesenchymal stem cells (MSCs). While BMP9 has been recognized for its potent osteogenic capabilities, NGF’s role in bone tissue engineering is less und...

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Bibliographic Details
Main Authors: Junyu Liu, Kun Yang, Gang Li, Yinghui Tan
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Mesenchymal stem cells
BMP9
NGF
Osteogenic differentiation
Tissue engineering
Online Access:https://doi.org/10.1186/s13018-025-05669-4
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https://doi.org/10.1186/s13018-025-05669-4

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