Genetic Variations Affect Chemotherapy Outcomes: A Role of the Spindle-assembly Checkpoint

Genetic Variations Affect Chemotherapy Outcomes: A Role of the Spindle-assembly Checkpoint

Cancer patients suffer from complicated chemotoxicity. Pharmacogenomics can help stratify patients by predicting their response to treatment and susceptibility toward severe side effects. The spindle-assembly checkpoint (SAC) is an important pathway that is activated by platinum and taxane compounds...

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Bibliographic Details
Main Authors: Sinjini Sarkar, Ranita Pal, Trisha Choudhury, Manisha Vernekar, Partha Nath, Vilas D. Nasare
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-04-01
Series:Indian Journal of Public Health
Subjects:
budding uninhibited by benzimidazoles 3
carboplatin
ovarian cancer
paclitaxel
spindle-assembly checkpoint
Online Access:https://journals.lww.com/10.4103/ijph.ijph_809_23
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https://journals.lww.com/10.4103/ijph.ijph_809_23

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