Profile of Serogroup Y Meningococcal Infections in Canada: Implications for Vaccine Selection

Canada is a leader in establishing routine infant immunization programs against meningococcal C disease. Currently, all provinces have routine programs to provide meningococcal C conjugate vaccines to infants and children. The result of the existing programs has been a decrease in serogroup C incide...

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Main Authors: Nicole Le Saux, Julie A Bettinger, Susan Wootton, Scott A Halperin, Wendy Vaudry, David W Scheifele, Raymond Tsang
Format: Article
Language:English
Published: Wiley 2009-01-01
Series:Canadian Journal of Infectious Diseases and Medical Microbiology
Online Access:http://dx.doi.org/10.1155/2009/871071
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author Nicole Le Saux
Julie A Bettinger
Susan Wootton
Scott A Halperin
Wendy Vaudry
David W Scheifele
Raymond Tsang
author_facet Nicole Le Saux
Julie A Bettinger
Susan Wootton
Scott A Halperin
Wendy Vaudry
David W Scheifele
Raymond Tsang
author_sort Nicole Le Saux
collection DOAJ
description Canada is a leader in establishing routine infant immunization programs against meningococcal C disease. Currently, all provinces have routine programs to provide meningococcal C conjugate vaccines to infants and children. The result of the existing programs has been a decrease in serogroup C incidence. The second most common vaccine-preventable serogroup in Canada is serogroup Y, the incidence of which has been stable. The availability of a quadrivalent conjugate vaccine against serogroups A, C, Y and W135 focuses attention on serogroup Y disease as it becomes relatively more prominent as a cause of vaccine-preventable invasive meningococcal disease. This vaccine was licensed in November 2006 but is not routinely used except in Nunavut, New Brunswick and Prince Edward Island. To allow a better understanding of the ‘value added’ by a serogroup Y-containing vaccine, it is necessary to have a contemporary profile of Y disease in Canada. In the present paper, recent surveillance data on invasive meningococcal disease across Canada are summarized.
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series Canadian Journal of Infectious Diseases and Medical Microbiology
spelling doaj-art-74e52b0bf9cf4702944a76b120c8a9f52025-02-03T01:06:19ZengWileyCanadian Journal of Infectious Diseases and Medical Microbiology1712-95322009-01-01204e130e13410.1155/2009/871071Profile of Serogroup Y Meningococcal Infections in Canada: Implications for Vaccine SelectionNicole Le Saux0Julie A Bettinger1Susan Wootton2Scott A Halperin3Wendy Vaudry4David W Scheifele5Raymond Tsang6Children’s Hospital of Eastern Ontario Research Institute and the University of Ottawa, Ottawa, Ontario, CanadaVaccine Evaluation Center, BC Children’s Hospital and the University of British Columbia, Vancouver, British Columbia, CanadaUniversity of Texas Health Science Center, Houston, Texas, USAClinical Trials Research Center, IWK Health Centre and Dalhousie University, Halifax, Nova Scotia, CanadaStollery Children’s Hospital and University of Alberta, Edmonton, Alberta, CanadaVaccine Evaluation Center, BC Children’s Hospital and the University of British Columbia, Vancouver, British Columbia, CanadaNational Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba, CanadaCanada is a leader in establishing routine infant immunization programs against meningococcal C disease. Currently, all provinces have routine programs to provide meningococcal C conjugate vaccines to infants and children. The result of the existing programs has been a decrease in serogroup C incidence. The second most common vaccine-preventable serogroup in Canada is serogroup Y, the incidence of which has been stable. The availability of a quadrivalent conjugate vaccine against serogroups A, C, Y and W135 focuses attention on serogroup Y disease as it becomes relatively more prominent as a cause of vaccine-preventable invasive meningococcal disease. This vaccine was licensed in November 2006 but is not routinely used except in Nunavut, New Brunswick and Prince Edward Island. To allow a better understanding of the ‘value added’ by a serogroup Y-containing vaccine, it is necessary to have a contemporary profile of Y disease in Canada. In the present paper, recent surveillance data on invasive meningococcal disease across Canada are summarized.http://dx.doi.org/10.1155/2009/871071
spellingShingle Nicole Le Saux
Julie A Bettinger
Susan Wootton
Scott A Halperin
Wendy Vaudry
David W Scheifele
Raymond Tsang
Profile of Serogroup Y Meningococcal Infections in Canada: Implications for Vaccine Selection
Canadian Journal of Infectious Diseases and Medical Microbiology
title Profile of Serogroup Y Meningococcal Infections in Canada: Implications for Vaccine Selection
title_full Profile of Serogroup Y Meningococcal Infections in Canada: Implications for Vaccine Selection
title_fullStr Profile of Serogroup Y Meningococcal Infections in Canada: Implications for Vaccine Selection
title_full_unstemmed Profile of Serogroup Y Meningococcal Infections in Canada: Implications for Vaccine Selection
title_short Profile of Serogroup Y Meningococcal Infections in Canada: Implications for Vaccine Selection
title_sort profile of serogroup y meningococcal infections in canada implications for vaccine selection
url http://dx.doi.org/10.1155/2009/871071
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