Exploiting Cancer Dormancy Signaling Mechanisms in Epithelial Ovarian Cancer Through Spheroid and Organoid Analysis

Exploiting Cancer Dormancy Signaling Mechanisms in Epithelial Ovarian Cancer Through Spheroid and Organoid Analysis

Epithelial ovarian cancer (EOC) exhibits a unique mode of metastasis, involving spheroid formation in the peritoneum. Our research on EOC spheroid cell biology has provided valuable insights into the signaling plasticity associated with metastasis. We speculate that EOC cells modify their biology be...

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Bibliographic Details
Main Authors: Emily J. Tomas, Yudith Ramos Valdes, Jennifer Davis, Bart Kolendowski, Adrian Buensuceso, Gabriel E. DiMattia, Trevor G. Shepherd
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Cells
Subjects:
epithelial ovarian cancer
high-grade serous
spheroids
organoids
cancer dormancy
transcriptome
Online Access:https://www.mdpi.com/2073-4409/14/2/133
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