Familial hypercholesterolaemia with early-onset coronary artery disease and recurrent in-stent restenosis associated with the LDLR gene c.428G>A mutation: a case report

Familial hypercholesterolaemia with early-onset coronary artery disease and recurrent in-stent restenosis associated with the LDLR gene c.428G>A mutation: a case report

BackgroundFamilial hypercholesterolaemia (FH) is characterised by significantly elevated low-density lipoprotein cholesterol (LDL-C) levels and early-onset coronary artery disease. Additionally, clopidogrel resistance is observed in approximately 30%–50% of individuals globally. Among FH patients wi...

Full description

Saved in:
Bibliographic Details
Main Authors: Chengpeng Zhang, Hui Li, Wei Zhang, Jian Huang, Jing Zhu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
familial hypercholesterolaemia
LDL receptor gene mutation
early-onset coronary artery disease
recurrent in-stent restenosis
PCSK9 inhibitors
precision medicine
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2025.1573543/full
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://www.frontiersin.org/articles/10.3389/fcvm.2025.1573543/full

Similar Items