The effectiveness and safety of ofatumumab for the treatment of pemphigus vulgaris: a cohort study based on a registry database

The effectiveness and safety of ofatumumab for the treatment of pemphigus vulgaris: a cohort study based on a registry database

BackgroundOfatumumab, a fully human anti-CD20 monoclonal antibody administered subcutaneously and indicated for multiple sclerosis, might theoretically be effective for patients with pemphigus vulgaris (PV).ObjectiveTo evaluate the effectiveness and safety of ofatumumab in patients with PV.MethodsTh...

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Main Authors: Xiwen Zhang, Yiyi Wang, Ping Tan, Xingli Zhou, Yue Xiao, Xun Feng, Jishu Li, Mintong Wei, Min Zou, Gyeongah Kim, Lu Jiang, Xiaohong Li, Jinqiu Wang, Mi Wang, Wei Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Immunology
Subjects:
pemphigus
therapy
ofatumumab
CD20 monoclonal antibody
B cell depletion
biologics
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1537334/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2025.1537334/full

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