Network pharmacology combined with experimental verification for exploring the potential mechanism of phellodendrine against depression
Abstract The anti-inflammatory effect of phellodendrine (PHE), derived from Phellodendri Chinensis Cortex, has been verified in previous studies. Major depressive disorder (MDD) is associated with immune dysregulation and inflammatory processes. This study aimed to explore the therapeutic effects of...
Saved in:
Main Authors: | Lili Hu, Na Wu, Jue Wang, Donghui Cai |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2025-01-01
|
Series: | Scientific Reports |
Subjects: | |
Online Access: | https://doi.org/10.1038/s41598-024-84771-9 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Network pharmacology-based screening of the active ingredients and mechanisms of Cymbaria daurica against diabetes mellitus
by: Ruyu Shi, et al.
Published: (2023-11-01) -
Exploration of the mechanism of Lithospermum erythrorhizon oil in treating atopic dermatitis based on network pharmacology and experimental validation of the PI3K-Akt pathway regulation
by: Weisheng Hu, et al.
Published: (2025-01-01) -
Elucidating the pharmacological foundations and mechanisms of the Sihai Shuyu formula in treating Graves’ disease through integrated serum metabolomics and network pharmacology with molecular docking techniques
by: Xiaoju Liu, et al.
Published: (2025-01-01) -
RETRACTED: Mechanism of action of Asparagus officinalis extract against multiple myeloma using bioinformatics tools, in silico and in vitro study
by: Yanju Li, et al.
Published: (2023-05-01) -
High-intensity acute noise exposure causes anxiety in female rats by inducing hippocampal neuron apoptosis
by: Yifei Song, et al.
Published: (2025-02-01)