Network pharmacology combined with experimental verification for exploring the potential mechanism of phellodendrine against depression

Abstract The anti-inflammatory effect of phellodendrine (PHE), derived from Phellodendri Chinensis Cortex, has been verified in previous studies. Major depressive disorder (MDD) is associated with immune dysregulation and inflammatory processes. This study aimed to explore the therapeutic effects of...

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Bibliographic Details
Main Authors: Lili Hu, Na Wu, Jue Wang, Donghui Cai
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-024-84771-9
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