Resveratrol improved atherosclerosis by increasing LDLR levels via the EGFR-ERK1/2 signaling pathway

Abstract Background and aims Atherosclerosis (AS) is a complex and chronic vascular disease and elevated low-density lipoprotein cholesterol (LDL-C) level is one of its primary causative factors. As a key surface receptor, low-density lipoprotein receptor (LDLR) plays an essential role in LDL-C clea...

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Main Authors: Dandan Hu, Litian Wang, Lin Qi, Xiangxuan Yang, Yamin Jin, Huailiu Yin, Yewei Huang, Jun Sheng, Xuanjun Wang
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Lipids in Health and Disease
Subjects:
Online Access:https://doi.org/10.1186/s12944-025-02585-8
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