Anuric Acute Kidney Injury in Chronic Myeloid Leukemia: A Rare Complication Case
This report describes a rare case of anuric acute kidney injury related to suspected urate nephropathy in a 23-year-old male with chronic phase of Chronic Myeloid Leukemia (CML). The patient presented with anuria and limb edema, with a history of imatinib-treated CML. Investigations revealed probabl...
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| Format: | Article |
| Language: | English |
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Interna Publishing
2024-10-01
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| Series: | Acta Medica Indonesiana |
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| Online Access: | https://actamedindones.org/index.php/ijim/article/view/2614 |
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| author | Angela Kimberly Tjahjadi Artaria Tjempakasari |
| author_facet | Angela Kimberly Tjahjadi Artaria Tjempakasari |
| author_sort | Angela Kimberly Tjahjadi |
| collection | DOAJ |
| description | This report describes a rare case of anuric acute kidney injury related to suspected urate nephropathy in a 23-year-old male with chronic phase of Chronic Myeloid Leukemia (CML). The patient presented with anuria and limb edema, with a history of imatinib-treated CML. Investigations revealed probable urate crystals causing bilateral hydronephrosis and hydroureters. Management included fluid restriction to maintain euvolemic status, hypouricemic agents, urinary alkalinization, urgent hemodialysis for acute kidney injury, and blood product transfusions to address haematological imbalances. The continued use of imatinib and aforementioned treatments resulted in the restoration of renal function depicted through normalization of serum urea, creatinine and uric acid levels. This case highlights the importance of meticulous assessment and management of anuric acute kidney injury in CML patients to ensure a positive outcome. |
| format | Article |
| id | doaj-art-74443acf01cc44dc98f664a5620e30db |
| institution | Kabale University |
| issn | 0125-9326 2338-2732 |
| language | English |
| publishDate | 2024-10-01 |
| publisher | Interna Publishing |
| record_format | Article |
| series | Acta Medica Indonesiana |
| spelling | doaj-art-74443acf01cc44dc98f664a5620e30db2025-01-27T04:12:06ZengInterna PublishingActa Medica Indonesiana0125-93262338-27322024-10-01564700Anuric Acute Kidney Injury in Chronic Myeloid Leukemia: A Rare Complication CaseAngela Kimberly Tjahjadi0Artaria Tjempakasari1Department of Internal Medicine, Faculty of Medicine, Universitas Airlangga, Surabaya, IndonesiaNephrology Division, Department of Internal Medicine, Faculty of Medicine Universitas Airlangga - Dr. Soetomo General Academic Hospital, Surabaya, IndonesiaThis report describes a rare case of anuric acute kidney injury related to suspected urate nephropathy in a 23-year-old male with chronic phase of Chronic Myeloid Leukemia (CML). The patient presented with anuria and limb edema, with a history of imatinib-treated CML. Investigations revealed probable urate crystals causing bilateral hydronephrosis and hydroureters. Management included fluid restriction to maintain euvolemic status, hypouricemic agents, urinary alkalinization, urgent hemodialysis for acute kidney injury, and blood product transfusions to address haematological imbalances. The continued use of imatinib and aforementioned treatments resulted in the restoration of renal function depicted through normalization of serum urea, creatinine and uric acid levels. This case highlights the importance of meticulous assessment and management of anuric acute kidney injury in CML patients to ensure a positive outcome.https://actamedindones.org/index.php/ijim/article/view/2614anuriaacute kidney injurychronic myeloid leukemia |
| spellingShingle | Angela Kimberly Tjahjadi Artaria Tjempakasari Anuric Acute Kidney Injury in Chronic Myeloid Leukemia: A Rare Complication Case Acta Medica Indonesiana anuria acute kidney injury chronic myeloid leukemia |
| title | Anuric Acute Kidney Injury in Chronic Myeloid Leukemia: A Rare Complication Case |
| title_full | Anuric Acute Kidney Injury in Chronic Myeloid Leukemia: A Rare Complication Case |
| title_fullStr | Anuric Acute Kidney Injury in Chronic Myeloid Leukemia: A Rare Complication Case |
| title_full_unstemmed | Anuric Acute Kidney Injury in Chronic Myeloid Leukemia: A Rare Complication Case |
| title_short | Anuric Acute Kidney Injury in Chronic Myeloid Leukemia: A Rare Complication Case |
| title_sort | anuric acute kidney injury in chronic myeloid leukemia a rare complication case |
| topic | anuria acute kidney injury chronic myeloid leukemia |
| url | https://actamedindones.org/index.php/ijim/article/view/2614 |
| work_keys_str_mv | AT angelakimberlytjahjadi anuricacutekidneyinjuryinchronicmyeloidleukemiaararecomplicationcase AT artariatjempakasari anuricacutekidneyinjuryinchronicmyeloidleukemiaararecomplicationcase |