Drosophila AHR limits tumor growth and stem cell proliferation in the intestine [version 2; peer review: 2 approved, 2 approved with reservations]

Background The aryl hydrocarbon receptor (AHR) plays important roles in intestinal homeostasis, limiting tumour growth and promoting differentiation in the intestinal epithelium. Spineless, the Drosophila homolog of AHR, has only been studied in the context of development but not in the adult intest...

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Bibliographic Details
Main Authors: Brigitta Stockinger, Jean-Paul Vincent, Alex P. Gould, Nicola Laura Diny, Jiawei Sun, Minghua Tsai, Michael Shapiro, Cyrille Alexandre, Ying Li, Adrien Franchet
Format: Article
Language:English
Published: Wellcome 2025-03-01
Series:Wellcome Open Research
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Online Access:https://wellcomeopenresearch.org/articles/10-38/v2
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