Association of plasma biomarkers of Alzheimer’s pathology and neurodegeneration with gait performance in older adults

Association of plasma biomarkers of Alzheimer’s pathology and neurodegeneration with gait performance in older adults

Abstract Background Declining gait performance is seen in aging individuals, due to neural and systemic factors. Plasma biomarkers provide an accessible way to assess evolving brain changes; non-specific neurodegeneration (NfL, GFAP) or evolving Alzheimer’s disease (Aβ 42/40 ratio, P-Tau181). Method...

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Main Authors: Farwa Ali, Jeremy A. Syrjanen, Dan J. Figdore, Walter K. Kremers, Michelle M. Mielke, Clifford R. Jack, David S. Knopman, Prashanthi Vemuri, Jonathan Graff-Radford, B. Gwen Windham, Leland R. Barnard, Ronald C. Petersen, Alicia Algeciras-Schimnich
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Communications Medicine
Online Access:https://doi.org/10.1038/s43856-024-00713-6
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https://doi.org/10.1038/s43856-024-00713-6

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