A Novel Prehydrated Porcine-Derived Acellular Dermal Matrix: A Histological and Clinical Evaluation

It is well known that soft tissue quality and quantity around dental implants is of paramount importance for later peri-implant health. For this purpose, the clinical and histological outcomes of the peri-implant mucosa, following soft tissue augmentation for soft tissue improvement with a novel pre...

Full description

Saved in:
Bibliographic Details
Main Authors: Andreas van Orten, Werner Goetz, Hakan Bilhan
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:International Journal of Biomaterials
Online Access:http://dx.doi.org/10.1155/2024/7322223
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832546138937360384
author Andreas van Orten
Werner Goetz
Hakan Bilhan
author_facet Andreas van Orten
Werner Goetz
Hakan Bilhan
author_sort Andreas van Orten
collection DOAJ
description It is well known that soft tissue quality and quantity around dental implants is of paramount importance for later peri-implant health. For this purpose, the clinical and histological outcomes of the peri-implant mucosa, following soft tissue augmentation for soft tissue improvement with a novel prehydrated porcine acellular dermal matrix graft (PPADMG) in conjunction with simultaneous implant placement, were evaluated in this case series. Twenty-two patients were included in the study. They underwent a late implant placement protocol combined with PPADMG for soft tissue augmentation. A punch biopsy was taken at the time of uncovery of the submerged healed implant after a mean of 157 days healing time. Supracrestal soft tissue height (STH) was measured at the time of implant placement and uncovery. All sites showed a clinical increase in STH. The histological structure of the biopsies resembled a similar structure as found in the healthy oral mucosa. No unexpected tissue reactions could be found. Within the limits of this clinical and histological study, it may be concluded that STH improvement with this novel porcine-derived acellular dermal matrix, in combination with simultaneous implant placement, is a viable option to create a peri-implant tissue thickness and stability.
format Article
id doaj-art-741189621e0f4bc497ea6abc576a0e2d
institution Kabale University
issn 1687-8795
language English
publishDate 2024-01-01
publisher Wiley
record_format Article
series International Journal of Biomaterials
spelling doaj-art-741189621e0f4bc497ea6abc576a0e2d2025-02-03T07:23:47ZengWileyInternational Journal of Biomaterials1687-87952024-01-01202410.1155/2024/7322223A Novel Prehydrated Porcine-Derived Acellular Dermal Matrix: A Histological and Clinical EvaluationAndreas van Orten0Werner Goetz1Hakan Bilhan2Private Dental Practice Do24Policlinic of OrthodonticsDepartment of PeriodontologyIt is well known that soft tissue quality and quantity around dental implants is of paramount importance for later peri-implant health. For this purpose, the clinical and histological outcomes of the peri-implant mucosa, following soft tissue augmentation for soft tissue improvement with a novel prehydrated porcine acellular dermal matrix graft (PPADMG) in conjunction with simultaneous implant placement, were evaluated in this case series. Twenty-two patients were included in the study. They underwent a late implant placement protocol combined with PPADMG for soft tissue augmentation. A punch biopsy was taken at the time of uncovery of the submerged healed implant after a mean of 157 days healing time. Supracrestal soft tissue height (STH) was measured at the time of implant placement and uncovery. All sites showed a clinical increase in STH. The histological structure of the biopsies resembled a similar structure as found in the healthy oral mucosa. No unexpected tissue reactions could be found. Within the limits of this clinical and histological study, it may be concluded that STH improvement with this novel porcine-derived acellular dermal matrix, in combination with simultaneous implant placement, is a viable option to create a peri-implant tissue thickness and stability.http://dx.doi.org/10.1155/2024/7322223
spellingShingle Andreas van Orten
Werner Goetz
Hakan Bilhan
A Novel Prehydrated Porcine-Derived Acellular Dermal Matrix: A Histological and Clinical Evaluation
International Journal of Biomaterials
title A Novel Prehydrated Porcine-Derived Acellular Dermal Matrix: A Histological and Clinical Evaluation
title_full A Novel Prehydrated Porcine-Derived Acellular Dermal Matrix: A Histological and Clinical Evaluation
title_fullStr A Novel Prehydrated Porcine-Derived Acellular Dermal Matrix: A Histological and Clinical Evaluation
title_full_unstemmed A Novel Prehydrated Porcine-Derived Acellular Dermal Matrix: A Histological and Clinical Evaluation
title_short A Novel Prehydrated Porcine-Derived Acellular Dermal Matrix: A Histological and Clinical Evaluation
title_sort novel prehydrated porcine derived acellular dermal matrix a histological and clinical evaluation
url http://dx.doi.org/10.1155/2024/7322223
work_keys_str_mv AT andreasvanorten anovelprehydratedporcinederivedacellulardermalmatrixahistologicalandclinicalevaluation
AT wernergoetz anovelprehydratedporcinederivedacellulardermalmatrixahistologicalandclinicalevaluation
AT hakanbilhan anovelprehydratedporcinederivedacellulardermalmatrixahistologicalandclinicalevaluation
AT andreasvanorten novelprehydratedporcinederivedacellulardermalmatrixahistologicalandclinicalevaluation
AT wernergoetz novelprehydratedporcinederivedacellulardermalmatrixahistologicalandclinicalevaluation
AT hakanbilhan novelprehydratedporcinederivedacellulardermalmatrixahistologicalandclinicalevaluation