Seizure-Induced Regulations of Amyloid-β, STEP61, and STEP61 Substrates Involved in Hippocampal Synaptic Plasticity
Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by progressive cognitive decline. Pathologic accumulation of soluble amyloid-β (Aβ) oligomers impairs synaptic plasticity and causes epileptic seizures, both of which contribute to cognitive dysfunction in AD. However, whether se...
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Main Authors: | Sung-Soo Jang, Sara E. Royston, Gunhee Lee, Shuwei Wang, Hee Jung Chung |
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Format: | Article |
Language: | English |
Published: |
Wiley
2016-01-01
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Series: | Neural Plasticity |
Online Access: | http://dx.doi.org/10.1155/2016/2123748 |
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