The Potential Association of Later Initiation of Oral/Enteral Nutrition on Euthyroid Sick Syndrome in Burn Patients
Objective. The aim of this study was to determine if early initiation of oral/enteral nutrition in burn patients minimizes the drop in fT3 levels, reduces the potential for euthyroid sick syndrome (ESS), and shortens the length of hospital stay (LHS). Subjects and Methods. We retrospectively evaluat...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | International Journal of Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2013/707360 |
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| author | Joaquín Pérez-Guisado Jesús M. de Haro-Padilla Luis F. Rioja Leo C. DeRosier Jorge I. de la Torre |
| author_facet | Joaquín Pérez-Guisado Jesús M. de Haro-Padilla Luis F. Rioja Leo C. DeRosier Jorge I. de la Torre |
| author_sort | Joaquín Pérez-Guisado |
| collection | DOAJ |
| description | Objective. The aim of this study was to determine if early initiation of oral/enteral nutrition in burn patients minimizes the drop in fT3 levels, reduces the potential for euthyroid sick syndrome (ESS), and shortens the length of hospital stay (LHS). Subjects and Methods. We retrospectively evaluated the statistical association of serum fT3, fT4, and TSH at the first (2nd–5th day) and second sample collection (9th–12th day) after the burn injury in 152 burn patients. Three groups were established depending on time of initiation of the oral/enteral nutrition: <24 h before the injury (Group 1), 24–48 h after the injury (Group 2), and >48 h after the injury (Group 3). Results. They were expressed as mean ± standard deviation. We found that LHS and the fT3 levels were statistically different in the 3 groups. The LHS (in days) was, respectively, in each group, 16.77±4.56, 21.98±4.86, and 26.06±5.47. Despite the quantifiable drop in fT3, ESS was present only at the first sample collection (2.61±0.92 days) in Group 3, but there was no group with ESS at the second sample collection (9.89±1.01 days). Our data suggest that early initiation of nutritional supplementation decreases the length of hospitalization and is associated with decreasing fT3 serum concentration depression. Conclusion. Early initiation of oral/enteral nutrition counteracts ESS and improves the LHS in burn patients. |
| format | Article |
| id | doaj-art-73fa843cac0c4f8c8751c84a859b925f |
| institution | Kabale University |
| issn | 1687-8337 1687-8345 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Endocrinology |
| spelling | doaj-art-73fa843cac0c4f8c8751c84a859b925f2025-02-03T07:26:08ZengWileyInternational Journal of Endocrinology1687-83371687-83452013-01-01201310.1155/2013/707360707360The Potential Association of Later Initiation of Oral/Enteral Nutrition on Euthyroid Sick Syndrome in Burn PatientsJoaquín Pérez-Guisado0Jesús M. de Haro-Padilla1Luis F. Rioja2Leo C. DeRosier3Jorge I. de la Torre4Service of Plastic, Aesthetic and Reconstructive Surgery, Reina Sofía University Hospital, Avenida Menéndez Pidal s/n, 14004 Córdoba, SpainService of Plastic, Aesthetic and Reconstructive Surgery, Reina Sofía University Hospital, Avenida Menéndez Pidal s/n, 14004 Córdoba, SpainService of Plastic, Aesthetic and Reconstructive Surgery, Reina Sofía University Hospital, Avenida Menéndez Pidal s/n, 14004 Córdoba, SpainDivision of Plastic Surgery, University of Alabama at Birmingham, 510 20th Street S, Birmingham, AL 35294-3411, USADivision of Plastic Surgery, University of Alabama at Birmingham, 510 20th Street S, Birmingham, AL 35294-3411, USAObjective. The aim of this study was to determine if early initiation of oral/enteral nutrition in burn patients minimizes the drop in fT3 levels, reduces the potential for euthyroid sick syndrome (ESS), and shortens the length of hospital stay (LHS). Subjects and Methods. We retrospectively evaluated the statistical association of serum fT3, fT4, and TSH at the first (2nd–5th day) and second sample collection (9th–12th day) after the burn injury in 152 burn patients. Three groups were established depending on time of initiation of the oral/enteral nutrition: <24 h before the injury (Group 1), 24–48 h after the injury (Group 2), and >48 h after the injury (Group 3). Results. They were expressed as mean ± standard deviation. We found that LHS and the fT3 levels were statistically different in the 3 groups. The LHS (in days) was, respectively, in each group, 16.77±4.56, 21.98±4.86, and 26.06±5.47. Despite the quantifiable drop in fT3, ESS was present only at the first sample collection (2.61±0.92 days) in Group 3, but there was no group with ESS at the second sample collection (9.89±1.01 days). Our data suggest that early initiation of nutritional supplementation decreases the length of hospitalization and is associated with decreasing fT3 serum concentration depression. Conclusion. Early initiation of oral/enteral nutrition counteracts ESS and improves the LHS in burn patients.http://dx.doi.org/10.1155/2013/707360 |
| spellingShingle | Joaquín Pérez-Guisado Jesús M. de Haro-Padilla Luis F. Rioja Leo C. DeRosier Jorge I. de la Torre The Potential Association of Later Initiation of Oral/Enteral Nutrition on Euthyroid Sick Syndrome in Burn Patients International Journal of Endocrinology |
| title | The Potential Association of Later Initiation of Oral/Enteral Nutrition on Euthyroid Sick Syndrome in Burn Patients |
| title_full | The Potential Association of Later Initiation of Oral/Enteral Nutrition on Euthyroid Sick Syndrome in Burn Patients |
| title_fullStr | The Potential Association of Later Initiation of Oral/Enteral Nutrition on Euthyroid Sick Syndrome in Burn Patients |
| title_full_unstemmed | The Potential Association of Later Initiation of Oral/Enteral Nutrition on Euthyroid Sick Syndrome in Burn Patients |
| title_short | The Potential Association of Later Initiation of Oral/Enteral Nutrition on Euthyroid Sick Syndrome in Burn Patients |
| title_sort | potential association of later initiation of oral enteral nutrition on euthyroid sick syndrome in burn patients |
| url | http://dx.doi.org/10.1155/2013/707360 |
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