Cryopreserving 3D cell culture models of Alzheimer’s disease in hydrogel microbeads

Cryopreserving 3D cell culture models of Alzheimer’s disease in hydrogel microbeads

Abstract Long-term preservation of fully differentiated human neurons poses a longstanding challenge in neuroscience research. Numerous cellular disease models have been established using cultured human neuronal cells, including our three-dimensional (3D) human neural cell culture model of Alzheimer...

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Bibliographic Details
Main Authors: Jae Jung Kim, Matthias Hebisch, Sang Su Kwak, Monica Zheng, Shreya Nuli, Jun-Seok Bae, Emma Brand, Rudolph E. Tanzi, Daniel Irimia, Doo Yeon Kim
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Hydrogel
Extracellular matrix
Neurodegeneration
Alzheimer’s disease
Online Access:https://doi.org/10.1038/s41598-025-94810-8
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https://doi.org/10.1038/s41598-025-94810-8

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