Peripheral Giant Cell Granuloma Associated with a Dental Implant: A Case Report and Review of the Literature
The peripheral giant cell granuloma (PGCG) is a nonneoplastic lesion commonly caused by local irritation. This report describes a 46-year-old Caucasian male who presented with a PGCG associated with a dental implant. The dental implant was originally placed in August 2012. Ten months later, the pati...
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Case Reports in Dentistry |
| Online Access: | http://dx.doi.org/10.1155/2015/697673 |
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| author | Amy Louise Brown Paulo Camargo de Moraes Marcelo Sperandio Andresa Borges Soares Vera Cavalcanti Araújo Fabrício Passador-Santos |
| author_facet | Amy Louise Brown Paulo Camargo de Moraes Marcelo Sperandio Andresa Borges Soares Vera Cavalcanti Araújo Fabrício Passador-Santos |
| author_sort | Amy Louise Brown |
| collection | DOAJ |
| description | The peripheral giant cell granuloma (PGCG) is a nonneoplastic lesion commonly caused by local irritation. This report describes a 46-year-old Caucasian male who presented with a PGCG associated with a dental implant. The dental implant was originally placed in August 2012. Ten months later, the patient presented with a well-circumscribed lesion associated with and covering the implant, at which time the lesion was excised. Four months later, due to recurrence of the lesion, a deeper and wider excisional biopsy with curettage of the adjacent bone was performed. No evidence of recurrence has been reported after 12 months of follow-up. Immunohistochemistry, using the antibody CD68, was performed to investigate the origin of the multinucleated giant cells, with their immunophenotype being similar to those of other giant cell lesions, including central giant cell granuloma, foreign-body reactions, and granulomatous reactions to infectious agents. |
| format | Article |
| id | doaj-art-73c56fee4d7e4a48b226322d3d019fd8 |
| institution | Kabale University |
| issn | 2090-6447 2090-6455 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Dentistry |
| spelling | doaj-art-73c56fee4d7e4a48b226322d3d019fd82025-02-03T01:01:40ZengWileyCase Reports in Dentistry2090-64472090-64552015-01-01201510.1155/2015/697673697673Peripheral Giant Cell Granuloma Associated with a Dental Implant: A Case Report and Review of the LiteratureAmy Louise Brown0Paulo Camargo de Moraes1Marcelo Sperandio2Andresa Borges Soares3Vera Cavalcanti Araújo4Fabrício Passador-Santos5Department of Pathology, São Leopoldo Mandic Institute and Research Centre, 13045-755 Campinas, SP, BrazilDepartment of Oral Medicine and Oral Surgery, São Leopoldo Mandic Institute and Research Centre, 13045-755 Campinas, SP, BrazilDepartment of Pathology, São Leopoldo Mandic Institute and Research Centre, 13045-755 Campinas, SP, BrazilDepartment of Pathology, São Leopoldo Mandic Institute and Research Centre, 13045-755 Campinas, SP, BrazilDepartment of Pathology, São Leopoldo Mandic Institute and Research Centre, 13045-755 Campinas, SP, BrazilDepartment of Pathology, São Leopoldo Mandic Institute and Research Centre, 13045-755 Campinas, SP, BrazilThe peripheral giant cell granuloma (PGCG) is a nonneoplastic lesion commonly caused by local irritation. This report describes a 46-year-old Caucasian male who presented with a PGCG associated with a dental implant. The dental implant was originally placed in August 2012. Ten months later, the patient presented with a well-circumscribed lesion associated with and covering the implant, at which time the lesion was excised. Four months later, due to recurrence of the lesion, a deeper and wider excisional biopsy with curettage of the adjacent bone was performed. No evidence of recurrence has been reported after 12 months of follow-up. Immunohistochemistry, using the antibody CD68, was performed to investigate the origin of the multinucleated giant cells, with their immunophenotype being similar to those of other giant cell lesions, including central giant cell granuloma, foreign-body reactions, and granulomatous reactions to infectious agents.http://dx.doi.org/10.1155/2015/697673 |
| spellingShingle | Amy Louise Brown Paulo Camargo de Moraes Marcelo Sperandio Andresa Borges Soares Vera Cavalcanti Araújo Fabrício Passador-Santos Peripheral Giant Cell Granuloma Associated with a Dental Implant: A Case Report and Review of the Literature Case Reports in Dentistry |
| title | Peripheral Giant Cell Granuloma Associated with a Dental Implant: A Case Report and Review of the Literature |
| title_full | Peripheral Giant Cell Granuloma Associated with a Dental Implant: A Case Report and Review of the Literature |
| title_fullStr | Peripheral Giant Cell Granuloma Associated with a Dental Implant: A Case Report and Review of the Literature |
| title_full_unstemmed | Peripheral Giant Cell Granuloma Associated with a Dental Implant: A Case Report and Review of the Literature |
| title_short | Peripheral Giant Cell Granuloma Associated with a Dental Implant: A Case Report and Review of the Literature |
| title_sort | peripheral giant cell granuloma associated with a dental implant a case report and review of the literature |
| url | http://dx.doi.org/10.1155/2015/697673 |
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