Comparative Protective Effects of N-Acetylcysteine, N-Acetyl Methionine, and N-Acetyl Glucosamine against Paracetamol and Phenacetin Therapeutic Doses–Induced Hepatotoxicity in Rats

Comparative Protective Effects of N-Acetylcysteine, N-Acetyl Methionine, and N-Acetyl Glucosamine against Paracetamol and Phenacetin Therapeutic Doses–Induced Hepatotoxicity in Rats

Background and Aims. Both paracetamol (PA) and phenacetin (PH) are analgesic and antipyretic agents. Part of phenacetin therapeutic activity is attributed to its metabolism into paracetamol. Paracetamol causes direct hepatic oxidative stress damage. The present study aimed to investigate the possibl...

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Bibliographic Details
Main Authors: Tahia H. Saleem, Nagwa Abo El-Maali, Mohammed H. Hassan, Nahed A. Mohamed, Nashwa A. M. Mostafa, Emaad Abdel-Kahaar, Azza S. Tammam
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:International Journal of Hepatology
Online Access:http://dx.doi.org/10.1155/2018/7603437
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http://dx.doi.org/10.1155/2018/7603437

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