Chronic Eosinophilic Leukemia—Not Otherwise Specified (NOS) in the Background of a Large Cell Lymphoma

Clonal eosinophilic disorders are rare among hematological malignancies. Most eosinophilia tends to be due to secondary causes such as infections, hypersensitivity conditions, drug reactions, and connective tissue disorders. The presence of a primary clonal eosinophilic disorder such as chronic eosi...

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Main Authors: Wilson I. Gonsalves, Rong He, Animesh Pardanani, Vinay Gupta, Jacob P. Smeltzer, Curtis A. Hanson, Thomas E. Witzig
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Case Reports in Hematology
Online Access:http://dx.doi.org/10.1155/2013/458303
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author Wilson I. Gonsalves
Rong He
Animesh Pardanani
Vinay Gupta
Jacob P. Smeltzer
Curtis A. Hanson
Thomas E. Witzig
author_facet Wilson I. Gonsalves
Rong He
Animesh Pardanani
Vinay Gupta
Jacob P. Smeltzer
Curtis A. Hanson
Thomas E. Witzig
author_sort Wilson I. Gonsalves
collection DOAJ
description Clonal eosinophilic disorders are rare among hematological malignancies. Most eosinophilia tends to be due to secondary causes such as infections, hypersensitivity conditions, drug reactions, and connective tissue disorders. The presence of a primary clonal eosinophilic disorder such as chronic eosinophilic leukemia—not otherwise specified (NOS) in the presence of a synchronous large cell lymphoma—is rare making the diagnosis challenging. We present a case of a 51-year-old female with the aforementioned presentation and demonstrate the extensive workup performed to identify the diagnosis.
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institution Kabale University
issn 2090-6560
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language English
publishDate 2013-01-01
publisher Wiley
record_format Article
series Case Reports in Hematology
spelling doaj-art-7368f145d6eb4e1b81a850ed71b0d1d12025-02-03T01:10:16ZengWileyCase Reports in Hematology2090-65602090-65792013-01-01201310.1155/2013/458303458303Chronic Eosinophilic Leukemia—Not Otherwise Specified (NOS) in the Background of a Large Cell LymphomaWilson I. Gonsalves0Rong He1Animesh Pardanani2Vinay Gupta3Jacob P. Smeltzer4Curtis A. Hanson5Thomas E. Witzig6Division of Hematology, Department of Medicine, Mayo Clinic, First Street SW, Rochester, MN 55905, USADivision of Hematopathology, Department of Laboratory Medicine and Pathology, Rochester, MN 55905, USADivision of Hematology, Department of Medicine, Mayo Clinic, First Street SW, Rochester, MN 55905, USADivision of Hematology, Department of Medicine, Mayo Clinic, First Street SW, Rochester, MN 55905, USADivision of Hematology, Department of Medicine, Mayo Clinic, First Street SW, Rochester, MN 55905, USADivision of Hematopathology, Department of Laboratory Medicine and Pathology, Rochester, MN 55905, USADivision of Hematology, Department of Medicine, Mayo Clinic, First Street SW, Rochester, MN 55905, USAClonal eosinophilic disorders are rare among hematological malignancies. Most eosinophilia tends to be due to secondary causes such as infections, hypersensitivity conditions, drug reactions, and connective tissue disorders. The presence of a primary clonal eosinophilic disorder such as chronic eosinophilic leukemia—not otherwise specified (NOS) in the presence of a synchronous large cell lymphoma—is rare making the diagnosis challenging. We present a case of a 51-year-old female with the aforementioned presentation and demonstrate the extensive workup performed to identify the diagnosis.http://dx.doi.org/10.1155/2013/458303
spellingShingle Wilson I. Gonsalves
Rong He
Animesh Pardanani
Vinay Gupta
Jacob P. Smeltzer
Curtis A. Hanson
Thomas E. Witzig
Chronic Eosinophilic Leukemia—Not Otherwise Specified (NOS) in the Background of a Large Cell Lymphoma
Case Reports in Hematology
title Chronic Eosinophilic Leukemia—Not Otherwise Specified (NOS) in the Background of a Large Cell Lymphoma
title_full Chronic Eosinophilic Leukemia—Not Otherwise Specified (NOS) in the Background of a Large Cell Lymphoma
title_fullStr Chronic Eosinophilic Leukemia—Not Otherwise Specified (NOS) in the Background of a Large Cell Lymphoma
title_full_unstemmed Chronic Eosinophilic Leukemia—Not Otherwise Specified (NOS) in the Background of a Large Cell Lymphoma
title_short Chronic Eosinophilic Leukemia—Not Otherwise Specified (NOS) in the Background of a Large Cell Lymphoma
title_sort chronic eosinophilic leukemia not otherwise specified nos in the background of a large cell lymphoma
url http://dx.doi.org/10.1155/2013/458303
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