Systemic S100A8/A9 in patients with moderate to severe acute ischemic stroke: Exploratory analysis of inflammation and functional outcome

Systemic S100A8/A9 in patients with moderate to severe acute ischemic stroke: Exploratory analysis of inflammation and functional outcome

Introduction: S100A8/A9, a danger-associated molecular pattern (DAMP), is released from leukocytes, mainly neutrophils, and augments inflammation and tissue damage. The role of systemic plasma levels of S100A8/A9 in stroke-related inflammation and its association with clinical outcome lacks sufficie...

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Main Authors: Christoph Vollmuth, Felipe A. Montellano, Cornelia Fiessler, Fabian Essig, Christian Hametner, Alexander M. Kollikowski, Vivian Vogt, Mirko Pham, Peter U. Heuschmann, Karl Georg Haeusler, Guido Stoll, Hermann Neugebauer, Michael K. Schuhmann
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:Brain, Behavior, & Immunity - Health
Subjects:
Blood-based biomarker
S100A8/A9
Calprotectin
Inflammation
Prognosis
Danger-associated molecular patterns
Online Access:http://www.sciencedirect.com/science/article/pii/S2666354625000997
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