A dynamic study of protein secretion and aggregation in the secretory pathway.

A dynamic study of protein secretion and aggregation in the secretory pathway.

Precise coordination of protein biogenesis, traffic and homeostasis within the early secretory compartment (ESC) is key for cell physiology. As a consequence, disturbances in these processes underlie many genetic and chronic diseases. Dynamic imaging methods are needed to follow the fate of cargo pr...

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Bibliographic Details
Main Authors: Maria Francesca Mossuto, Sara Sannino, Davide Mazza, Claudio Fagioli, Milena Vitale, Edgar Djaha Yoboue, Roberto Sitia, Tiziana Anelli
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0108496
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