A novel missense variant of FBN1 gene in a Sardinian family with Marfan syndrome: a case report

BackgroundMarfan Syndrome (MS) is a connective tissue disorder, an autosomal dominant condition mostly caused by variants in the FBN1 gene, which encodes for fibrillin-1 protein. Anomalies in the gene lead to a wide variety of clinical manifestations, including disorders of the cardiac, ocular and m...

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Main Authors: Marina Marsan, Mattia Brutti, F. Meloni, M. Marica, C. Soddu, F. Lai, D. Martorana, S. Savasta
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Pediatrics
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Online Access:https://www.frontiersin.org/articles/10.3389/fped.2025.1549504/full
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