Patient‐Derived Melanoma Immune‐Tumoroids as a Platform for Precise High throughput Drug Screening

Patient‐Derived Melanoma Immune‐Tumoroids as a Platform for Precise High throughput Drug Screening

Abstract In vitro models are crucial in cancer research, but they must truthfully mimic in vivo tumors for clinical relevance. The development of unprecedent melanoma quadruple multicellular tumoroids (MCTs) is proposed comprising tumor cells, keratinocytes, fibroblasts, and monocytes that replicate...

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Bibliographic Details
Main Authors: Juliana Viegas, Sofia Costa, Sofia Dias, Catarina Leite Pereira, Bruno Sarmento
Format: Article
Language:English
Published: Wiley 2024-12-01
Series:Advanced Science
Subjects:
3D models
in vitro model
multicellular spheroids
patient‐derived
skin cancer
Online Access:https://doi.org/10.1002/advs.202408707
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