Morbidity of 200 Consecutive Cases of Hand-Assisted Laparoscopic Living Donor Nephrectomies: A Single-Center Experience

Background. Recipients of laparoscopically procured kidneys have been reported to have delayed graft function, a slower creatinine nadir, and potential significant complications. As the technique has evolved laparoscopic donor nephrectomy technique is becoming the gold standard for living donation....

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Main Authors: Pedro W. Baron, Ramzi Ben-Youssef, Okechukwu N. Ojogho, Arputharaj Kore, D. Duane Baldwin
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Journal of Transplantation
Online Access:http://dx.doi.org/10.1155/2012/121523
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author Pedro W. Baron
Ramzi Ben-Youssef
Okechukwu N. Ojogho
Arputharaj Kore
D. Duane Baldwin
author_facet Pedro W. Baron
Ramzi Ben-Youssef
Okechukwu N. Ojogho
Arputharaj Kore
D. Duane Baldwin
author_sort Pedro W. Baron
collection DOAJ
description Background. Recipients of laparoscopically procured kidneys have been reported to have delayed graft function, a slower creatinine nadir, and potential significant complications. As the technique has evolved laparoscopic donor nephrectomy technique is becoming the gold standard for living donation. Study Design. We retrospectively reviewed the data of the first 200 hand-assisted laparoscopic living donor nephrectomies performed between January 2003 and February 2009. The initial 41 donors and their recipients (Group 1) were compared to the next 159 donors and their recipients (Group 2). The estimated blood loss, serum creatinine at discharge and 6 months, and the incidence of delayed graft function and perioperative complications were analyzed. Results. The median donor serum creatinine at discharge and 6 months was 1.2 mg/dL in each group. None of the laparoscopic procedures required conversion to an open procedure, and none of the donors required perioperative blood transfusion. The median recipient serum creatinine at 6 months after transplant was 1.2 mg/dL for each group. No ischemic ureteral complications related to the laparoscopic technique were seen. Conclusions. HALDN with meticulous surgical technique allows kidney procurement with very low morbidity and no mortality. This improved safety and decreased invasiveness from laparoscopic approach may further decrease morbidity of the procedure and increase organ donation.
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spelling doaj-art-7284ab3487ae42fcaa56d706383cb6ee2025-02-03T01:09:41ZengWileyJournal of Transplantation2090-00072090-00152012-01-01201210.1155/2012/121523121523Morbidity of 200 Consecutive Cases of Hand-Assisted Laparoscopic Living Donor Nephrectomies: A Single-Center ExperiencePedro W. Baron0Ramzi Ben-Youssef1Okechukwu N. Ojogho2Arputharaj Kore3D. Duane Baldwin4Transplantation Institute, Loma Linda University Medical Center, Loma Linda, CA 92354, USATransplantation Institute, Loma Linda University Medical Center, Loma Linda, CA 92354, USATransplantation Institute, Loma Linda University Medical Center, Loma Linda, CA 92354, USATransplantation Institute, Loma Linda University Medical Center, Loma Linda, CA 92354, USADepartment of Urology, Loma Linda University Medical Center, Loma Linda, CA 92354, USABackground. Recipients of laparoscopically procured kidneys have been reported to have delayed graft function, a slower creatinine nadir, and potential significant complications. As the technique has evolved laparoscopic donor nephrectomy technique is becoming the gold standard for living donation. Study Design. We retrospectively reviewed the data of the first 200 hand-assisted laparoscopic living donor nephrectomies performed between January 2003 and February 2009. The initial 41 donors and their recipients (Group 1) were compared to the next 159 donors and their recipients (Group 2). The estimated blood loss, serum creatinine at discharge and 6 months, and the incidence of delayed graft function and perioperative complications were analyzed. Results. The median donor serum creatinine at discharge and 6 months was 1.2 mg/dL in each group. None of the laparoscopic procedures required conversion to an open procedure, and none of the donors required perioperative blood transfusion. The median recipient serum creatinine at 6 months after transplant was 1.2 mg/dL for each group. No ischemic ureteral complications related to the laparoscopic technique were seen. Conclusions. HALDN with meticulous surgical technique allows kidney procurement with very low morbidity and no mortality. This improved safety and decreased invasiveness from laparoscopic approach may further decrease morbidity of the procedure and increase organ donation.http://dx.doi.org/10.1155/2012/121523
spellingShingle Pedro W. Baron
Ramzi Ben-Youssef
Okechukwu N. Ojogho
Arputharaj Kore
D. Duane Baldwin
Morbidity of 200 Consecutive Cases of Hand-Assisted Laparoscopic Living Donor Nephrectomies: A Single-Center Experience
Journal of Transplantation
title Morbidity of 200 Consecutive Cases of Hand-Assisted Laparoscopic Living Donor Nephrectomies: A Single-Center Experience
title_full Morbidity of 200 Consecutive Cases of Hand-Assisted Laparoscopic Living Donor Nephrectomies: A Single-Center Experience
title_fullStr Morbidity of 200 Consecutive Cases of Hand-Assisted Laparoscopic Living Donor Nephrectomies: A Single-Center Experience
title_full_unstemmed Morbidity of 200 Consecutive Cases of Hand-Assisted Laparoscopic Living Donor Nephrectomies: A Single-Center Experience
title_short Morbidity of 200 Consecutive Cases of Hand-Assisted Laparoscopic Living Donor Nephrectomies: A Single-Center Experience
title_sort morbidity of 200 consecutive cases of hand assisted laparoscopic living donor nephrectomies a single center experience
url http://dx.doi.org/10.1155/2012/121523
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