Postpartum Vaginal Blood Loss following Two Different Methods of Cervical Ripening

Eighty women undergoing induction of labor at the University of Calabar Teaching Hospital were recruited and randomly allocated into two treatment groups (40 each), to receive either serial 50 µg doses of misoprostol or intracervical Foley catheter. Vaginal blood loss was collected and measured usin...

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Main Authors: Okon Asuquo Okon, John Egede Ekabua
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Obstetrics and Gynecology International
Online Access:http://dx.doi.org/10.1155/2017/1678265
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author Okon Asuquo Okon
John Egede Ekabua
author_facet Okon Asuquo Okon
John Egede Ekabua
author_sort Okon Asuquo Okon
collection DOAJ
description Eighty women undergoing induction of labor at the University of Calabar Teaching Hospital were recruited and randomly allocated into two treatment groups (40 each), to receive either serial 50 µg doses of misoprostol or intracervical Foley catheter. Vaginal blood loss was collected and measured using an under buttocks plastic collection bag and by perineal pad weighing up to 6 hours postpartum. There were no significant differences between the two groups with respect to sociodemographic and obstetric characteristics. Comparison of blood loss in vaginal deliveries between the two groups revealed that subjects in the misoprostol group had significantly higher blood loss than subjects in the Foley catheter group (488 ± 222 versus 326 ± 106, p<0.05). In both groups, there was strong and statistically significant positive correlation between postpartum blood loss and induction delivery interval (r=0.75, p<0.0001; r=0.77, p<0.0001). There were no significant differences in maternal outcomes. In view of this, further study is required to ascertain if lower doses of misoprostol for induction of labor may result in lesser blood loss. This trial is registered with ISRCTN14479515.
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spelling doaj-art-723f7c6a87db47868c9991b4dbc93ed62025-02-03T06:45:20ZengWileyObstetrics and Gynecology International1687-95891687-95972017-01-01201710.1155/2017/16782651678265Postpartum Vaginal Blood Loss following Two Different Methods of Cervical RipeningOkon Asuquo Okon0John Egede Ekabua1Department of Obstetrics and Gynecology, Faculty of Medicine, University of Calabar, Calabar, Cross River State, NigeriaDepartment of Obstetrics and Gynecology, Faculty of Medicine, University of Calabar, Calabar, Cross River State, NigeriaEighty women undergoing induction of labor at the University of Calabar Teaching Hospital were recruited and randomly allocated into two treatment groups (40 each), to receive either serial 50 µg doses of misoprostol or intracervical Foley catheter. Vaginal blood loss was collected and measured using an under buttocks plastic collection bag and by perineal pad weighing up to 6 hours postpartum. There were no significant differences between the two groups with respect to sociodemographic and obstetric characteristics. Comparison of blood loss in vaginal deliveries between the two groups revealed that subjects in the misoprostol group had significantly higher blood loss than subjects in the Foley catheter group (488 ± 222 versus 326 ± 106, p<0.05). In both groups, there was strong and statistically significant positive correlation between postpartum blood loss and induction delivery interval (r=0.75, p<0.0001; r=0.77, p<0.0001). There were no significant differences in maternal outcomes. In view of this, further study is required to ascertain if lower doses of misoprostol for induction of labor may result in lesser blood loss. This trial is registered with ISRCTN14479515.http://dx.doi.org/10.1155/2017/1678265
spellingShingle Okon Asuquo Okon
John Egede Ekabua
Postpartum Vaginal Blood Loss following Two Different Methods of Cervical Ripening
Obstetrics and Gynecology International
title Postpartum Vaginal Blood Loss following Two Different Methods of Cervical Ripening
title_full Postpartum Vaginal Blood Loss following Two Different Methods of Cervical Ripening
title_fullStr Postpartum Vaginal Blood Loss following Two Different Methods of Cervical Ripening
title_full_unstemmed Postpartum Vaginal Blood Loss following Two Different Methods of Cervical Ripening
title_short Postpartum Vaginal Blood Loss following Two Different Methods of Cervical Ripening
title_sort postpartum vaginal blood loss following two different methods of cervical ripening
url http://dx.doi.org/10.1155/2017/1678265
work_keys_str_mv AT okonasuquookon postpartumvaginalbloodlossfollowingtwodifferentmethodsofcervicalripening
AT johnegedeekabua postpartumvaginalbloodlossfollowingtwodifferentmethodsofcervicalripening