Intravesical Botulinum Toxin for Persistent Autonomic Dysreflexia in a Pediatric Patient
Introduction. We present a novel case of persistent autonomic dysreflexia in a pediatric spinal cord injury patient treated successfully with intravesical botulinum toxin. Study Design. A retrospective chart review of one patient seen at the Children’s Hospital of Wisconsin from 2006 to 2012 was per...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Case Reports in Urology |
| Online Access: | http://dx.doi.org/10.1155/2016/4569684 |
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| author | Gina Lockwood Charles Durkee Travis Groth |
| author_facet | Gina Lockwood Charles Durkee Travis Groth |
| author_sort | Gina Lockwood |
| collection | DOAJ |
| description | Introduction. We present a novel case of persistent autonomic dysreflexia in a pediatric spinal cord injury patient treated successfully with intravesical botulinum toxin. Study Design. A retrospective chart review of one patient seen at the Children’s Hospital of Wisconsin from 2006 to 2012 was performed. Results. A pediatric spinal cord injury patient with known neurogenic bladder presented with severe hypertension consistent with autonomic dysreflexia. His symptoms and hypertension did not improve with conservative measures, and he necessitated ICU admission and antihypertensive drips. He was taken to the operating room for intravesical botulinum toxin for refractory bladder spasms. Following this, his symptoms abated, and he was weaned off IV antihypertensives and returned to his baseline state. His symptoms were improved for greater than six months. Conclusions. There are few treatment options for the management of refractory autonomic dysreflexia. Intravesical botulinum toxin has never been reported for this use. Dedicated research is warranted to assess its efficacy, as it was used successfully to abort autonomic dysreflexia in this patient. |
| format | Article |
| id | doaj-art-7237af636e324018a1364c510118cddc |
| institution | Kabale University |
| issn | 2090-696X 2090-6978 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Urology |
| spelling | doaj-art-7237af636e324018a1364c510118cddc2025-02-03T05:59:26ZengWileyCase Reports in Urology2090-696X2090-69782016-01-01201610.1155/2016/45696844569684Intravesical Botulinum Toxin for Persistent Autonomic Dysreflexia in a Pediatric PatientGina Lockwood0Charles Durkee1Travis Groth2Department of Urology, Medical College of Wisconsin, 9000 West Wisconsin Avenue, Milwaukee, WI 53226, USADepartment of Urology, Medical College of Wisconsin, 9000 West Wisconsin Avenue, Milwaukee, WI 53226, USADepartment of Urology, Medical College of Wisconsin, 9000 West Wisconsin Avenue, Milwaukee, WI 53226, USAIntroduction. We present a novel case of persistent autonomic dysreflexia in a pediatric spinal cord injury patient treated successfully with intravesical botulinum toxin. Study Design. A retrospective chart review of one patient seen at the Children’s Hospital of Wisconsin from 2006 to 2012 was performed. Results. A pediatric spinal cord injury patient with known neurogenic bladder presented with severe hypertension consistent with autonomic dysreflexia. His symptoms and hypertension did not improve with conservative measures, and he necessitated ICU admission and antihypertensive drips. He was taken to the operating room for intravesical botulinum toxin for refractory bladder spasms. Following this, his symptoms abated, and he was weaned off IV antihypertensives and returned to his baseline state. His symptoms were improved for greater than six months. Conclusions. There are few treatment options for the management of refractory autonomic dysreflexia. Intravesical botulinum toxin has never been reported for this use. Dedicated research is warranted to assess its efficacy, as it was used successfully to abort autonomic dysreflexia in this patient.http://dx.doi.org/10.1155/2016/4569684 |
| spellingShingle | Gina Lockwood Charles Durkee Travis Groth Intravesical Botulinum Toxin for Persistent Autonomic Dysreflexia in a Pediatric Patient Case Reports in Urology |
| title | Intravesical Botulinum Toxin for Persistent Autonomic Dysreflexia in a Pediatric Patient |
| title_full | Intravesical Botulinum Toxin for Persistent Autonomic Dysreflexia in a Pediatric Patient |
| title_fullStr | Intravesical Botulinum Toxin for Persistent Autonomic Dysreflexia in a Pediatric Patient |
| title_full_unstemmed | Intravesical Botulinum Toxin for Persistent Autonomic Dysreflexia in a Pediatric Patient |
| title_short | Intravesical Botulinum Toxin for Persistent Autonomic Dysreflexia in a Pediatric Patient |
| title_sort | intravesical botulinum toxin for persistent autonomic dysreflexia in a pediatric patient |
| url | http://dx.doi.org/10.1155/2016/4569684 |
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