18F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in Large-Vessel Vasculitis During Active and Inactive Disease Stages Is Associated with the Metabolic Profile, but Not the Macrophage-Related Cytokines: A Proof-of-Concept Study

18F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in Large-Vessel Vasculitis During Active and Inactive Disease Stages Is Associated with the Metabolic Profile, but Not the Macrophage-Related Cytokines: A Proof-of-Concept Study

Giant cell arteritis (GCA) is an autoimmune/autoinflammatory disease affecting large vessels in patients over 50 years old. The disease presents as an acute inflammatory response with two phenotypes, cranial GCA and large-vessel vasculitis (LV)-GCA, involving the thoracic aorta and its branches. 18F...

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Main Authors: Dimitris Anastasios Palamidas, Georgios Kalykakis, Dimitra Benaki, Loukas Chatzis, Ourania D. Argyropoulou, Panagiota Palla, Antonia Kollia, Pavlos Kafouris, Marinos Metaxas, Andreas V. Goules, Emmanuel Mikros, Konstantinos Kambas, Constantinos D. Anagnostopoulos, Athanasios G. Tzioufas
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Cells
Subjects:
giant cell arteritis
large vessel vasculitis
cytokines
metabolomics
18F-FDG PET-CT
Online Access:https://www.mdpi.com/2073-4409/13/22/1851
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