FABP4 as a therapeutic host target controlling SARS-CoV-2 infection

FABP4 as a therapeutic host target controlling SARS-CoV-2 infection

Abstract Host metabolic fitness is a critical determinant of infectious disease outcomes. Obesity, aging, and other related metabolic disorders are recognized as high-risk disease modifiers for respiratory infections, including coronavirus infections, though the underlying mechanisms remain unknown....

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Main Authors: Hatoon Baazim, Emre Koyuncu, Gürol Tuncman, M Furkan Burak, Lea Merkel, Nadine Bahour, Ezgi Simay Karabulut, Grace Yankun Lee, Alireza Hanifehnezhad, Zehra Firat Karagoz, Katalin Földes, Ilayda Engin, Ayse Gokce Erman, Sidika Oztop, Nazlican Filazi, Buket Gul, Ahmet Ceylan, Ozge Ozgenc Cinar, Fusun Can, Hahn Kim, Ali Al-Hakeem, Hui Li, Fatih Semerci, Xihong Lin, Erkan Yilmaz, Onder Ergonul, Aykut Ozkul, Gökhan S Hotamisligil
Format: Article
Language:English
Published: Springer Nature 2025-01-01
Series:EMBO Molecular Medicine
Subjects:
FABP4
SARS-CoV-2
COVID-19
Replication Organelles
Lipid Droplets
Online Access:https://doi.org/10.1038/s44321-024-00188-x
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https://doi.org/10.1038/s44321-024-00188-x

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