High throughput method for simultaneous screening of membrane permeability and toxicity for discovery of new cryoprotective agents
Abstract Cryoprotective agent (CPA) toxicity is the most limiting factor impeding cryopreservation of critically needed tissues and organs for transplantation and medical research. This limitation is in part due to the challenge of rapidly screening compounds to identify candidate molecules that are...
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Main Authors: | Nima Ahmadkhani, James D. Benson, Ali Eroglu, Adam Z. Higgins |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2025-01-01
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Series: | Scientific Reports |
Subjects: | |
Online Access: | https://doi.org/10.1038/s41598-025-85509-x |
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