High throughput method for simultaneous screening of membrane permeability and toxicity for discovery of new cryoprotective agents

Abstract Cryoprotective agent (CPA) toxicity is the most limiting factor impeding cryopreservation of critically needed tissues and organs for transplantation and medical research. This limitation is in part due to the challenge of rapidly screening compounds to identify candidate molecules that are...

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Bibliographic Details
Main Authors: Nima Ahmadkhani, James D. Benson, Ali Eroglu, Adam Z. Higgins
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-85509-x
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