Iodine activates NLRP3 inflammasomes in PBMCs of patients with autoimmune thyroiditis and regulates Th1 and Th17 cell differentiation

Iodine activates NLRP3 inflammasomes in PBMCs of patients with autoimmune thyroiditis and regulates Th1 and Th17 cell differentiation

Objectives: Inflammasomes are associated with various autoimmune diseases. Herein, we aimed to study the occurrence of inflammasomes in peripheral blood mononuclear cells (PBMCs) from patients with autoimmune thyroiditis (AIT), and the relationship between their abundance and the inflammatory respon...

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Bibliographic Details
Main Authors: Ying Wu, Qingling Guo, Yongping Liu, Xun Gong, Wei Sun, Yushu Li, Chenling Fan, Weiping Teng, Zhongyan Shan
Format: Article
Language:English
Published: Bioscientifica 2025-01-01
Series:Endocrine Connections
Subjects:
autoimmune thyroiditis
inflammasome
peripheral blood mononuclear cells
iodine
t cell subsets
Online Access:https://ec.bioscientifica.com/view/journals/ec/14/2/EC-24-0456.xml
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