R-loop formation contributes to mTORC1 activation-dependent DNA replication stress induced by p53 deficiency
DNA replication stress is a significant contributor to spontaneous DNA damage and genome instability. While the impact of p53 deficiency on increasing DNA replication stress is known, the specific molecular mechanism underlying this phenome...
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Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
China Science Publishing & Media Ltd.
2024-11-01
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Series: | Acta Biochimica et Biophysica Sinica |
Subjects: | |
Online Access: | https://www.sciengine.com/doi/10.3724/abbs.2024188 |
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